重视新型冠状病毒肺炎对心脏的损害

重视新型冠状病毒肺炎对心脏的损害(2020年第32卷第三期)

肖颖彬

(陆军军医大学第二附属医院全军心血管外科研究所,重庆400037

摘要 目前2019新型冠状病毒(2019-nCov)感染的肺炎疫情进入了一个严峻且复杂的局面,疫情防控和救治形势十分严峻。现新型冠状病毒肺炎NCP病情演化规律的认识,疾病确切的发病机理,尤其是发生重症化的机理尚不完全清楚。本文从肾素-血管紧张素系统RAS)分子通路的角度,以血管紧张素转换酶2ACE2)靶点,探讨2019-nCov可能对NCP患者的心脏损害及对心血管疾病患者的危害。

关键词 2019新型冠状病毒;新型冠状病毒肺炎血管紧张素转换酶2;心脏损害

中图分类】 RR511;R519.9;R54  文献标志码  A  

 

 

Pay attention to the heart damage of new coronavirus pneumonia

XIAO Yingbin

 

(Institute of Cardiovascular Surgery, The Second Affiliated Hospital of Army Medical University, Chongqing 400037, China)

Abstract At present, the epidemic of pneumonia caused by 2019 new coronavirus (2019-nCov) has entered a severe and complicated situation. The situation of epidemic prevention and control and treatment is very severe. The understanding of the evolution of the new coronavirus pneumonia (NCP) is now unclear. The exact pathogenesis of the disease, especially the mechanism of severe disease, is not fully understood. In this paper, from the perspective of Renin-angiotension system (Ras) molecular pathway, the target of ACE-2 was used to explore the possible cardiac damage and cardiovascular disease in patients with NCP in 2019-ncov.          

   key words 2019 novel coronavirus; novel coronavirus pneumonia; Angiotensin-converting enzyme 2; Heart damage; pathogenesis

 

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