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心脏磁共振多模态成像在肥厚性心肌病中的临床应用
李湘,师轲,杨志刚
0
(四川大学华西医院放射科)
摘要:
【摘要】 肥厚性心肌病(HCM)是一种具有遗传倾向,并以心肌肥厚为主要特征的原发性心肌病,也是青少年和运动员发生猝死的最主要原因。任何年龄阶段及种族均可患病,且临床表现、基因突变类型、病程进展都存在异质性,因此对本病的及时诊断、病情严重程度的评价及疾病预后的评估至关重要。心脏磁共振(CMR)作为重要的影像学检查技术对心脏结构、功能、心肌活性及分子影像方面的评价具有重要的意义。本文将对CMR多模态成像对HCM诊疗中的临床价值及研究进展做一综述。
关键词:  肥厚性心肌病  心肌活性  心脏磁共振  多模态成像  分子影像
DOI:
基金项目:心血管影像学临床及转化研究平台建设,四川大学华西医学院学科卓越发展1.3.5工程(ZYGD18013))
Clinical application of multimodality cardiac magnetic resonance imaging in hypertrophic cardiomyopathy
LI Xiang,SHI Ke,YANG Zhigang
(Department of Radiology, West China Hospital, Sichuan University)
Abstract:
【Abstract】Hypertrophic Cardiomyopathy (HCM) is a primary cardiomyopathy with a genetic tendency and characterized by myocardial hypertrophy. HCM also has been the leading cause of the sudden death of adolescent and athletes. It may occur at any age and race. Heterogeneity exists in clinical manifestations, types of genic mutations and the rate of progression of HCM. Hence, it is of vital importance to early diagnose the disease and evaluate its severity and prognosis. Cardiac Magnetic Resonance (CMR) as for an important examination method has significant implications for the evaluation of cardiac structure, function, myocardial viability and molecular imaging. This study aims to review the clinical value of CMR multimodality imaging in the establishment of diagnosis and treatment of HCM and the progress of research in recent years.
Key words:  Hypertrophic Cardiomyopathy  Myocardial activi  Cardiac Magnetic Resonance  Multimodality Imaging  Molecular imaging

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