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臭氧治疗肿瘤的研究进展
邱世香,赵茂林,胡文,刘康,钟立明
0
(川北医学院医学影像学院;南充市中心医院·川北医学院第二临床医学院组织工程与干细胞研究所;南充市中心医院·川北医学院第二临床医学院介入放射科)
摘要:
恶性肿瘤是目前危及人类健康的主要疾病之一,它不仅给患者及其家庭、社会带来巨大的经济压力,也是医学界尚未完全攻破的难题。臭氧的治疗性应用始于第一次世界大战期间。随着臭氧治疗椎间盘突出症、外周动脉阻塞性疾病、年龄相关性黄斑变性、牙科相关性疾病等的广泛应用,使其逐渐引起肿瘤学专家的关注。20世纪80年代,臭氧治疗就开始作为恶性肿瘤的一种辅助性治疗方法,但其有效性和机制尚未明确。本文从从体外实验、动物实验及临床研究三个方面对医用臭氧治疗肿瘤的研究进展作一综述,以探讨臭氧治疗肿瘤的有效性及其可能机制。
关键词:  臭氧治疗  肿瘤治疗  体内实验  体外实验
DOI:
基金项目:南充市研发资金项目(KY 16YFZJ0023)
Research progress of ozone therapy for tumor
QIU Shixiang,ZHAO Maolin,HU Wen,LIU Kang,ZHONG Liming
(School of Medical Imaging, North Sichuan Medical College;Institute of Tissue Engineering and Stem Cell Research, Nanchong Central Hospital, The Second Clinical College of North Sichuan Medical College;Department of Interventional Radiology, Nanchong Central Hospital, The Second Clinical College of North Sichuan Medical College)
Abstract:
Malignant tumor is one of the main diseases endangering human health at present. It not only brings great economic pressure to patients, their families and society, but also is a difficult problem that has not been completely solved in the medical field. Therefore, there is an urgent need to find a new and costeffective treatment for the benefit of the majority of tumor patients. At present, the combined use of multidisciplinary comprehensive therapy in the treatment of tumors has gradually become the consensus of the industry. The therapeutic application of ozone has a long history and began during the first World War. With the extensive application of ozone in the treatment of intervertebral disc herniation, peripheral artery obstructive disease, agerelated macular degeneration, dental related diseases and so on, ozone has gradually entered the field of vision of oncologists. Ozone therapy has been used as an auxiliary treatment for malignant tumors since the 1980s, but its effectiveness and mechanism are not yet clear. Combined with the relevant research of our group, and reviewing other reports at home and abroad, this paper will summarize the research progress of medical ozone in the treatment of tumor from three aspects: in vitro experiment, animal experiment and clinical research. To explore the effectiveness of ozone in the treatment of tumors and its possible mechanism.
Key words:  Ozone therapy  Cancer therapy  In vivo experiments  In vitro experiments

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