引用本文:[点击复制]
[点击复制]
【打印本页】 【在线阅读全文】【下载PDF全文】 查看/发表评论下载PDF阅读器关闭

←前一篇|后一篇→

过刊浏览    高级检索

本文已被:浏览 265次   下载 47 本文二维码信息
码上扫一扫!
冠心病冠脉优势型与血管病变数目及严重程度的相关性分析
赵玉杰,王岗,张静静,李佳媚,高雅,闫斌,苏丹
0
(西安交通大学第二附属医院重症医学科;西安交通大学第一附属医院临床研究中心;西安交通大学第二附属医院心内科)
摘要:
目的 探讨冠心病中冠脉优势型与血管病变数目及疾病严重程度的关系,为冠心病危重度预测及分级提供理论依据。方法 选取2010年7月~2014年4月西安交通大学第二附属医院确诊的冠心病患者1654例为研究对象,行单中心回顾性观察性研究。根据病变累及部位分为3组:单支血管病变组(n=465)、双支血管病变组(n=414)和三支血管病变组(n=775)。再根据冠脉优势型将所有患者分为两组:右冠优势型(n=1500)、非右冠优势型(左冠优势型和均衡型,n=154)(考虑后两者所占比例偏低,将其合并)。将年龄、性别、吸烟史、是否患高血压、糖尿病及高脂血症作为协变量,利用Logistic回归模型分析何种冠脉优势型是冠心病血管病变数目增加的可能危险因素;比较Gensini评分,探讨冠脉优势型和冠心病严重程度的关系。结果 右冠优势型患三支血管病变的可能性是非右冠优势型的1.681倍(OR=1.681;95% CI=1.096~2.579; P=0.017);但右冠优势型患双支血管病变的可能性与非右优势型比较,差异无〖JP2〗统计学意义(OR=1.212; 95%CI=0.781~1.880;P=0.392)。右冠优势型Gensini评分明显高于非右冠优势型(42.3±〖JP〗33.6 vs36.3±29.8,P=0.033)。结论 右冠优势型可能是三支血管病变的独立危险因素,并且右冠优势型会导致较严重的血管病变程度。
关键词:  冠心病  右冠优势型  三支血管病变  冠状动脉造影  Gensini评分
DOI:
基金项目:国家自然科学基金(81300116,81770057);陕西省科技计划青年科技新星项目(2015KJXX-06)
The relationship between coronary arterial dominance and the number of the vascular lesions and correlation analysis of the severity in patients with coronary artery disease
ZHAO Yujie,WANG Gang,ZHANG Jingjing,LI Jiamei,GAO Ya,YAN Bin,SU Dan
(Department of Critical Care Medicine, The Second Affiliated Hospital of Xi′an Jiaotong University;Department of Clinical Research Centre, The First Affiliated Hospital of Xi′an Jiaotong University;Department of Cardiology, The Second Affiliated Hospital of Xi′an Jiaotong University)
Abstract:
Objective To investigate the relationship between coronary arterial dominance and the number of the vascular lesions and correlation analysis of the severity in patients with coronary artery disease (CAD).Methods From July 2010 to April 2014, 1654 CAD patients were enrolled in our hospital. According to vascular lesions involving, CAD patients were divided into the onevessel disease (n = 465), the twovessel disease (including single left coronary artery lesion) n=414) and the three-vessel disease (n=775). After adjusting age, sex, smoking history, hypertension, diabetes and hyperlipidemia, the logistic regression model was used to analyze which type of coronary artery dominance (right coronary dominance, nonright coronary dominance) was the possible risk factor for the increase of the number of coronary artery disease. Gensini score was compared to explore the relationship between coronary dominant types the severity of coronary artery disease.Results In the multivariate logistic regression model, possibility of right dominant type with threevessel disease was 1.681 times more likely than nonright dominant type (Odds Ratio [OR]= 1.681, 95% confidence interval [CI], 1.096-2.579, P= 0.017), and the difference was statistically significant. However, there was no significant difference in the incidence of doublevessel disease between right dominant and nonright dominant types (OR=1.212, 95% CI, 0.781-1.880, P= 0.392). The Gensini score of right coronary dominant group was significantly higher than nonright coronary dominant group(42.3±33.6 vs 36.3±29.8,P=0.033). Conclusion Rightcoronary dominance may be an independent risk factor for threevessel disease, and rightcoronary dominance may lead to a more severity of coronary artery disease.
Key words:  Coronary heart disease  Right coronary arterial dominance  Three-vessel disease  Coronary angiography  Gensini score

用微信扫一扫

用微信扫一扫