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术前外周血中调节性T淋巴细胞水平与卵巢癌的关系研究进展
陈明星,李均,冯露,李兰,胡辉权,徐凡
0
(川北医学院第二临床医学院·南充市中心医院妇产科)
摘要:
【摘要】 卵巢癌(ovarian cancer,OC)是妇科常见恶性肿瘤之一,其发病率及死亡率均居前列。卵巢癌早期症状不典型,发现时多数已是晚期。术前若能有相关血液指标对卵巢癌进行预测,可使患者获得更好的治疗方案。近年研究发现大多数卵巢癌患者存在术前外周血中调节性T淋巴细胞(regulatory T cells,Tregs)比例升高的现象,且其升高程度与卵巢癌临床病理分期及预后明显有关。本文就术前外周血中调节性T淋巴细胞水平与卵巢癌的关系予以综述。
关键词:  卵巢癌  调节性T淋巴细胞  临床病理分期
DOI:
基金项目:四川省教育厅项目;;南充市科技局项目;南充市社科联项目
The research progress of relationship between regulatory T cells level in peripheral blood and ovarian cancer
CHEN Mingxing,LI Jun,FENG Lu,LI Lan,HU Huiquan,XU Fan
(Department of Obstetrics and Gynecology, The Second Clinical Medical College of North Sichuan Medical College, Nanchong Central Hospital)
Abstract:
【Abstract】 Ovarian cancer is among the most common gynecologic tumors, and its morbidity and mortality were among the highest in gynecologic tumors. Ovarian cancer is mostly diagnosed very late or in advanced stages, because its early symptoms are atypical. The patient will get better treatment if there are some blood indexs can predict ovarian cancer before surgery. Nowadays, some studies have reported that the preoperative regulatory T cells percentage in ovarian cancer were higher than benign ovarian tumor and healthy control, and its correlated with the prognosis and clinicopathological staging of ovarian cancer. In this paper, the relationship between preoperative regulatory T cells level and ovarian cancer will be reviewed.
Key words:  Ovarian cancer  Regulatory T cells  Tregs

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