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重症急性胰腺炎恢复期胃瘫发生情况及相关因素分析
赵群远,宋肖肖,杨春燕
0
(昆明医科大学 1.第二附属医院急诊内科;2.公共卫生学院流行病学与卫生统计学教研室)
摘要:
【摘要】 目的 探讨重症急性胰腺炎(SAP)恢复期胃瘫(GS)发生的相关影响因素。方法 纳入2013年5月~2016年5月我院189例SAP患者,分析恢复期GS发生情况和相关独立危险因素。结果 189例患者中,GS发生率794%(15例);年龄、性别、BMI、糖尿病史、后期白蛋白水平、外科手术治疗、后期血糖含量、焦虑抑郁、发生心血管并发症和动脉血pH是影响SAP恢复期发生GS的单因素(P<005);多因素logistic回归分析显示,其中性别(OR=33181,P=0003,95CI% 2502~457105)、糖尿病史(OR=12354,P=0011,95CI% 1863~81941)、外科手术(OR=16232,P=0004,95CI% 2697~97710)、焦虑抑郁(OR=1530,P=0021,95CI% 0940~2489)是SAP恢复期发生GS的独立危险因素,而后期白蛋白水平(OR=0289,P=0043,95CI% 0014~0768)是SAP恢复期GS的保护因素。结论 女性、有糖尿病史、外科手术和焦虑抑郁是SAP恢复期发生GS的危险因素,而后期高白蛋白水平是其保护因素,采取对症护理、加强原发病治疗和肠内营养支持等措施,利于预防GS发生。
关键词:  重症急性胰腺炎  恢复期  胃瘫  影响因素
DOI:
基金项目:
The incidence and related factors of gastroparesis in convalescence of severe acute pancreatitis
ZHAO Qunyuan,SONG Xiaoxiao,YANG Chunyan
(1.Department of Emergency Medicine, The Second Affiliated Hospital of Kunming Medical University;2.Department of Epidemiology and Health Statistics, Kunming Medical University School of Public Health)
Abstract:
【Abstract】 Objective To analyze the incidence and related factors of gastroparesis (GS) in convalescence of severe acute pancreatitis (SAP). Methods 189 patients with SAP treated in our hospital from May 2013 to May 2016 were enrolled in the study. The incidence and related independent risk factors of GS in convalescence of SAP were analyzed. ResultsThe incidence of GS in the 189 patients was 794% (15 cases). Age, gender, BMI, history of diabetes mellitus, albumin levels in later period, surgical treatment, the blood glucose levels, anxiety and depression, the incidence of cardiovascular complications and arterial blood pH were the single factors influencing the incidence of GS in convalescence of SAP (P<005). Multivariate logistic regression analysis showed that gender (OR=33181, P=0003, 95CI% 2502457105), history of diabetes mellitus (OR=12354, P=0011, 95CI% 186381941), surgery (OR=16232, P=0004, 95CI% 269797710) and anxiety and depression (OR=1530, P=0021, 95CI% 09402489) were the independent risk factors for GS in convalescence of SAP, and albumin level in later period (OR=0289, P=0043, 95CI% 00140768) was a protective factor for GS in convalescence of SAP. Conclusion Female, with history of diabetes mellitus, surgery, depression and anxiety are the risk factors for GS in convalescence of SAP, and high albumin level in later period is the protective factor. Adopting symptomatic nursing, strengthening the treatment of primary diseases and enteral nutrition support are conductive to prevention of GS.
Key words:  Severe acute pancreatitis  Convalescence  Gastroparesis  Influencing factors

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