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肺原位腺癌和微浸润腺癌的高分辨CT影像形态学特征研究
李红,段萍,汪俐杉,银文杰
0
(成都市第一人民医院放射科;成都市第一人民医院肿瘤科)
摘要:
【摘要】目的 探讨肺原位腺癌(adenocarcinoma in situ,AIS)和微浸润腺癌(minimally invasive adenocarcinoma, MIA)的高分辨CT形态学特征,与周围血管位置变化关系。方法〓选取127例经手术病理证实的AIS和MIA患者,分为AIS组(48例)和MIA组(79例),总结患者术前胸部的高分辨CT图像特征及术后的病理学资料,并分析其组间差异。结果 两组术前肺部小结节病灶的大小、密度及是否有血管穿行组间差异均有统计学意义(P<005);AIS组小结节最大直径平均值为(91±08)mm,MIA组的最大值径为(96±11)mm,组间比较差异有统计学意义(P<005);AIS组中小结节密度不均,呈混合性磨玻璃结节(mixed groundglass nodule,mGGN)有10例,占208%,MIA组mGGN为31例,占392%,组间比较差异有统计学意义(P<005);AIS组中结节周围有血管穿行的有13例,占333%, MIA组中结节周围血管穿行的有41例,占518%,两组比较差异均有明显统计学意义(P<005)。结论 肺部小结节的高分辨CT形态学特征可以对AIS及MIA这两种病理亚型进行预判断,可为患者提供手术方案及预后治疗提供帮助。
关键词:  肺原位腺癌  微浸润腺癌  形态学特征  CT
DOI:
基金项目:成都市科技惠民项目
High Resolution CT study on morphological feature of the adenocarcinoma in situ and minimally invasive adenocarcinoma
LI Hong,DUAN Ping,WANG Lishan,YIN Wenjie
(Department of Radiology, Chengdu First People's Hospital;Department of Oncology, Chengdu First People's Hospital)
Abstract:
【Abstract】 Objective To investigate HighResolution (HRCT) morphological feature of adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma(MIA),combined with the change of blood vessel location.Methods 127 AIS and MIA patients which confirmed by pathology and operation,Divided into two groups,Summarized the morphological feature of CT images before operation and pathological materials after operation.Results 48 cases of AIS and 79 cases of MIA were confirmed by pathology. The small pulmonary nodules'size, density and which passing through by vessels were significant in statistic (P<005).The averaging diameter of the lesion in the group of AIS was(91±08)mm. The MIA group was (96±11)mm, 10 cases of mixed groundglass nodule(mGGN) in AIS (208%),31 cases of mGGN in MIA (392%), 13 cases of which nodules passing through by vessles in AIS(333%), 41cases in MIA(518%). There were significant in statistic (P<005).Conclusion The analysis of the imaging features of the lesions in pulmonary can predict the AIS and MIA,It would be helpful to provide individualized surgery and postoperative treatment.
Key words:  Adenocarcinoma in situ  Minimally invasive adenocarcinoma  Morphological characteristics  CT

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