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攀枝花地区1214例新生儿感染性肺炎病原学特点分析
唐晓燕,陈艾,田春
0
(攀枝花学院附属医院儿科·攀枝花学院儿科教研室;西南医科大学附属医院儿科)
摘要:
【摘要】 目的 探讨攀枝花地区新生儿感染性肺炎患儿病原分布及特点,为临床预防及诊治提供参考依据。方法 回顾性分析 2010~2016年住院治疗的 1214例新生儿感染性肺炎的病原学特点。病原学来源包括鼻咽抽吸物进行细菌培养、血培养、TORCH、输血前检查,并对其特点进行分析。结果 1214例新生儿中397例于冬季入院,240例于夏季入院,冬季与夏季入院人数有统计学差异;标本送检率以血培养最高(8682%),痰培养最低(5470%);而异常细菌检出率以痰培养最高(4623%),血培养阳性率较低(285%)。有307例痰培养细菌异常检出阳性,其中检出肺炎克雷伯杆菌82株(2671%) ,金黄色葡萄球菌68株(2214%),大肠埃希菌 62 株(2020%)。血培养阳性前三位细菌为大肠埃希菌 8 株(2667%)、肺炎克雷伯杆菌6株(2000%)金黄色葡萄球菌4株(1333%)。结论 攀枝花地区新生儿感染性肺炎主要在冬季发病较多,肺炎克雷伯杆菌为本地区新生儿感染性肺炎住院患儿感染的首位致病菌。肺炎新生儿患者,痰培养阳性率高,针对性强,值得推广。
关键词:  病原学  新生儿  肺炎
DOI:
基金项目:四川省教育厅科研课题(17ZB0470);西南医科大学研究生重点课题(YZ15004);西南医科大学重点科研基金(20161205)
Pathogen detection of 1214 cases of hospitalized neonates with pneumonia
Tang Xiaoyan,Chen Ai,Tian Chun
(Department of Pediatric, The Affiliated Hospital of Panzhihua College;Department of Pediatric, The Affiliated Hospital of Southwest Medical University)
Abstract:
【Abstract】 Objective To investigate the distribution of pathogens of neonates with pneumonia from Panzhihua area. Methods Sputum specimens and blood specimens of 1214 neonates with pneumonia were collected from January 2010to December 2016 for sputum culture, blood culture, TORCH detection and examination before blood transfusion, which including IgM of TP, HCMV, HIV, HBV. Results The number of pneumoniae inpatients were higher in winter and lower in summer(P<005). For delivery rate concern, blood culture arrived to 8682% while sputum culture only to 5470%, but the highest positive bacteria detection rate belong to sputum culture(4623%). Among 307 positive cases, Klebsiella Pneumoniae was 82 cases(2671%), Staphylococcus aureus was 68 cases(2214%),and E.coliwas 62 cases (2020%),while the positive cases of the three bacteria from bkood culture was E.coli (2667%) , Klebsiella Pneumoniae (2000%), Staphylococcus aureus(1333%).Conclusions Sputum culture is worth of spreading for pathogen detection in neunates with pneumonia because its higher positive rate. The peak of neonates pneumonia is in winter, Klebsiella Pneumoniae is the major bacteria in inpatients neonates of Panzhihua area.
Key words:  Pathogen detection  Neonates  Pneumonia

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