引用本文:[点击复制]
[点击复制]
【打印本页】 【在线阅读全文】【下载PDF全文】 查看/发表评论下载PDF阅读器关闭

←前一篇|后一篇→

过刊浏览    高级检索

本文已被:浏览 28次   下载 7 本文二维码信息
码上扫一扫!
宫颈癌患者人乳头状瘤病毒感染与阴道细菌感染的相关性
郭冰杰,杨彩梅
0
(北京中医医院顺义医院妇产科)
摘要:
【摘要】 目的 探讨宫颈癌患者人乳头状瘤病毒(HPV)感染与阴道细菌感染的相关性。方法 2014年2月~2017年1月选择来院诊治的宫颈癌患者150例作为观察组,同期选择非宫颈癌的慢性宫颈炎患者150例作为对照组,采集两组的阴道分泌物与宫颈标本,检测阴道细菌感染及其HPVDNA阳性情况。结果 观察组中检出HPVDNA感染90例,阳性率600%;对照组中检出HPVDNA感染40例,阳性率267%,观察组的HPVDNA阳性率明显高于对照组(P<005)。观察组中检出阴道细菌78例,检出率为520%,其中革兰阴性菌60例,革兰阳性菌18例;对照组中检出阴道细菌70例,检出率为467%,其中革兰阴性菌55例,革兰阳性菌15例,两组阴道细菌感染检出率对比差异无统计学意义(X2=0087,P>005)。在观察组中,HPVDNA感染状态与阴道细菌感染的结果差别无统计学意义(X2=0872,P>005)。直线相关分析宫颈癌患者HPV感染与阴道细菌感染无明显相关性(r=0092,P>005)。结论 宫颈癌患者的HPV阳性率高于宫颈炎患者,且阴道分泌物中致病菌检出率较高,革兰阴性菌检出率居首位,阴道细菌感染与HPV感染协同因素促进宫颈癌的发生尚待进一步研究。
关键词:  人乳头状瘤病毒  阴道细菌感染  宫颈癌  革兰阴性菌  慢性宫颈炎
DOI:
基金项目:国家卫生计生委医药卫生科技发展研究中心项目(W2016CWBJ04)
Correlation between human papilloma virus infection and vaginal bacterial infection in cervical cancer
GUO Bingjie,YANG Caimei
(Department of Gynaecology and Obstetrics, Beijing Chinese Medicine Hospital of Shunyi Branch)
Abstract:
【Abstract】 Objective To investigate the correlation between human papilloma virus infection and vaginal bacterial(HPV) infection in cervical cancer. Methods From February 2014 to January 2017, 150 cervical cancer patients in our hospital were selected as the observation group. 150 patients of chronic cervicitis with non cervical cancer were selected as the control group. The vaginal and cervical samples in the two groups were collected. The HPVDNA positive infection and detection of vaginal bacteria were recorded. Results In the observation group, there were detected in 90 cases of HPVDNA infection. The positive rate of the observation group was 60%. The control group were detected in 40 cases of HPVDNA infection and the positive rate was 267%. The positive rate of HPVDNA in observation group was significantly higher than the control group (P<005). In the observation group, there were 78 cases of vaginal bacteria and the detection rate was 52%. There were 60 cases of Gram negative bacteria and 18 cases of Gram positive bacteria. In the control group, there were 70 cases of vaginal bacteria and the detection rate was 467%. There were 55 cases of Gram negative bacteria and 15 cases of Gram positive bacteria. The vaginal bacterial infection detection rate of the two groups were not significant difference (X2=0087, P<005). In the observation group, there was no significant difference between HPVDNA infection status and vaginal bacterial infection (X2=0872, P>005). Linear correlation analysis showed that there was no correlation between HPV infection and vaginal bacterial infection in cervical cancer patients (r=0092, P>005). Conclusion The positive rate of HPV in patients with cervical cancer is higher than that in chronic cervicitis patients. The pathogen detection rate is higher and the detection rate of Gram negative bacteria in the first place. The vagina bacterial infection of HPV infection to promote the development of cervical cancer needs further analysis.
Key words:  Human papillomavirus  Vaginal bacterial infection  Cervical cancer  Gram negative bacteria  Chronic cervicitis

用微信扫一扫

用微信扫一扫