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Sox2在妇科肿瘤中的研究进展
李沛琳,刘钧
0
(川北医学院 病理教研室,四川 南充 637000;川北医学院 附属医院病理科,四川 南充 637000)
摘要:
妇科肿瘤严重危害女性健康,尤其妇科恶性肿瘤,是造成发展中国家女性癌症死亡的最常见原因。Sox2是一种多能性调节因子,越来越多的证据表明,Sox2异常表达与妇科肿瘤的发生发展密切相关。本文将Sox2在妇科肿瘤中的研究现状进行综述。
关键词:  Sox2  妇科肿瘤  宫颈癌  子宫内膜癌  卵巢癌
DOI:
基金项目:四川省教育厅课题(12ZB225)
Current research of the role of Sox2 in gynecologic tumor
LI Peilin,LIU Jun
(Department of Pathology, North Sichuan Medical College, Nanchong 637000, Sichuan, China;Department of Pathology, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan, China)
Abstract:
Gynecologic tumor is harm to women health. Gynecologic malignancies are a leading cause of cancerrelated death for women in developing countries. Many researches showed that Sox2 is a pluripotent regulator, and Sox2 abnormal expression is closely related to the development of gynecologic tumors. In this paper, we reviewed recent advances about the Sox2 gene in gynecologic tumors.
Key words:  Sox2  Gynecologic tumor  Cervical cancer  Endometrial cancer  Ovarian cancer

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