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藏族人群颈动脉内膜中层厚度影响因素的相关研究
严心,龚深圳,陈晓平,朱小江,李欣然,阳钰婕
0
(四川大学华西医院心血管内科)
摘要:
目的 探讨高原藏族人群颈动脉内膜中层厚度(CIMT)的超声检测的影响因素。方法 对四川省甘孜州藏族自治州的两个佛学院内的藏族僧侣和周边乡镇藏族非僧侣进行问卷调查、体格检查(身高、体重、腰围、臀围、血压测量等)、CIMT检测及留取空腹血多个相关生化指标检测等,共计1409名参与者。结果 ①按CIMT增厚与正常分组,年龄、舒张压(DBP)、收缩压(SDP)、腰围、臀围、空腹血糖、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高血压患病率、喝茶加盐率、经常摄入蔬菜率、僧侣比例、佛事活动时间均有显著性差异(P<0.05)。②按藏族僧侣与非僧侣分组比较,舒张压、体重指数(BMI)、腰围、空腹血糖、高密度脂蛋白胆固醇(HDL-C)、佛事活动时间及CIMT均有显著性差异(P<0.05)。③Logistic回归分析显示,年龄、收缩压、空腹血糖、食肉率、总胆固醇升高是CIMT增加的危险因素;而僧侣、佛事活动时间增加、HDL-C升高是CIMT的保护因素。结论 年龄、收缩压、腰臀比、空腹血糖、总胆固醇升高是藏族人群CIMT增高的危险因素,而僧侣、佛事活动时间增加、HDL-C升高是保护因素。
关键词:  颈动脉内膜中层厚度(CIMT)  高血压  藏族  僧侣  佛事活动
DOI:
基金项目:四川省科技支撑计划项目(2012SZ0131)
The study of influencing factors for carotid intima-media thickness in Tibetan people
YAN Xin,GONG Shenzhen,CHEN Xiaoping,ZHU Xiaojiang,LI Xinran,YANG Yujie
(Department of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, China)
Abstract:
Objective To investigate the influencing factors for carotid intimamedia thickness in Tibetan people. Methods 1409 participants were enrolled in the Tibetan autonomous prefecture of Ganzi, Sichuan Province, who were either Tibetan Buddhists or Tibetan ordinary residents. Standardized questionnaire, physical examination, fasting blood sampling and carotid ultrasonic inspection were performed. Results 1. When grouped into normal and increased CIMT, there were significant different in age, diastolic blood pressure(DBP), systolic blood pressure(SBP), waistline, hipline, fasting blood glucose(FBG), total cholesterol(TC), triglyceride(TG), LDL-L, Buddhism activity participation time, and rate of hypertension, drinking tea with salt, frequent intaking vegetables, and being Buddhists (all P<0.05). 2. When grouped into Buddhists and ordinary residents, there were significant different in DBP, BMI, waistline, FBG, HDL-C, Buddhism activity participation time, and CIMT. 3. Logistic regression analyses showed that increased CIMT was associated with age, waist to hip ratio (WHR), SBP, FBG and TC in Tibetan. Being Buddhists, longer Buddhism activities participation time and HDL-C performed the protective factors of the CIMT value in in Tibetan. Conclusion Age, SBP, WHR, FBG, TC are significant risk factors for CIMT in Tibetan. And Buddhism activity participation is an independent protective factor for CIMT in Tibetan.
Key words:  Carotid intima-media thickness  Hypertension  Tibetan  Buddhists  Buddhism activity participation

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